Global Spread of Mutant PfCRT and Its Pleiotropic Impact on Plasmodium falciparum Multidrug Resistance and Fitness

ABSTRACT The global spread of Plasmodium falciparum chloroquine resistance transporter (PfCRT) variant haplotypes earlier caused the widespread loss of chloroquine (CQ) efficacy.In Asia, novel PfCRT mutations that emerged on the Dd2 beanie allelic background have recently been implicated in high-level resistance to piperaquine, and N326S and I356T

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Internet Preaching as a New Format of Religious Communication

The article is devoted to the analysis of English-language Internet sermons presented in video format in the digital environment.According to the author, a video sermon is an innovative form of religious communication; its prevalence is determined both by the information technology development and by the possibility of prompt and large-scale broadc

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General Small-Signal Modeling and Parameter Optimization of the Soft Normally-Open Point Connected to the Distribution Network

The soft normally-open point (SNOP) is a multi-terminal power electronic device installed between two or more feeders in the low and medium voltage distribution network, which can adjust the active power and reactive power between the feeders.A small-signal model of SNOP connected to the distribution network is established.The model includes the li

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